Table of Contents

I. History

1. An Introduction to Extracorporeal Life Support

2. The Development of Prolonged Extracorporeal Circulation

II. Physiologic Basis for ECLS

3. Physiology of Extracorporeal Life Support

4. Coagulation, Anticoagulation, and the Interaction of Blood and Artificial Surfaces

5. ECMO: Hemodynamics, Perfusion, and Blood Volume

6. Principles and Practice of Venovenous Extracorporeal Membrane Oxygenation

7. ECLS and the Brain

8. ECLS and Fluids, Electrolytes and Renal Function

9. Extracorporeal Life Support and the Systemic Inflammatory Response

10. Extracorporeal Life Support in Liver Failure and Sepsis

III. Clinical Applications of ECLS

11. ECLS Technical Manuals

12. Devices

13. ECMO in the Hospital Setting

14. Vascular Access for Extracorporeal Organ Support

15. Emergencies During ECMO and Their Management

16. The Registry of the Extracorporeal Life Support Organization

IV. Neonatal ECLS

17. Management of Neonatal Respiratory Failure

18. Neonatal Selection Criteria for ECMO

19. Clinical Management of Neonates on Venoarterial ECMO

20. Management of Infants with Congenital Diaphragmatic Hernia using ECMO

21. Management of ECMO in Preterm Infants

22. Outcome and Followup of Neonates Treated with ECMO

V. Pediatric Respiratory Failure

23. Pediatric Respiratory Failure

24. ECLS for Children with Acute Respiratory Distress Syndrome

25. Management of Children with ECLS

26. Outcome following Pediatric ECMO

VI. Adults

27. Selection Criteria for Use of ECLS in Adults

28. Management of ECLS in Adult Respiratory Failure

29. Outcome and Follow-up of Adults Following Extracorporeal Life Support

VII. ECLS for Cardiac Support

30. Pediatric Cardiac Support: Physiology and Techniques

31. ECLS for Infants and Children with Cardiac Disease.  Overview and Examples

32. Extracorporeal Life Support Following Adult Open-Heart Surgery

33. Cardiopulmonary Support

VIII. Special Situations

34. Extracorporeal Life Support: How Can its Effectiveness be Studied?

35. Referral and Transport of ECMO Patients

36. Economics of Extracorporeal Life Support

37. Legal Considerations During ECLS

38. Ethics and ECMO

39. Regulatory Issues Related to Extracorporeal Life Support

40. Liquid Ventilation in the Setting of Severe Respiratory Failure

41. Intracorporeal Membrane Oxygenation and Carbon Dioxide Removal

42. Lung Transplantation and ECLS

43. Future of ECLS

IX. Appendix - ELSO Documents